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Stereoselective chemo-enzymatic oxidation routes for (1R,3E,7E,11S,12S)-3,7,18-dolabellatriene

The diterpene (1R,3E,7E,11S,12S)-3,7,18-dolabellatriene from the marine brown alga Dilophus spiralis belongs to the dolabellanes natural product family and has antimicrobial activity against multi-drug resistant Staphylococcus aureus. Recently, we generated a CotB2 diterpene synthase mutant (W288G),...

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Detalles Bibliográficos
Autores principales:	Görner, Christian, Hirte, Max, Huber, Stephanie, Schrepfer, Patrick, Brück, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602142/ https://www.ncbi.nlm.nih.gov/pubmed/26528263 http://dx.doi.org/10.3389/fmicb.2015.01115

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