Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding

The polymerase chain reaction (PCR) is one of the most widely used techniques in molecular biology. In combination with High Throughput Sequencing (HTS), PCR is widely used to quantify transcript abundance for RNA-seq, and in the context of analysis of T and B cell receptor repertoires. In this stud...

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Detalles Bibliográficos
Autores principales: Best, Katharine, Oakes, Theres, Heather, James M., Shawe-Taylor, John, Chain, Benny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602216/
https://www.ncbi.nlm.nih.gov/pubmed/26459131
http://dx.doi.org/10.1038/srep14629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602216/
https://www.ncbi.nlm.nih.gov/pubmed/26459131
http://dx.doi.org/10.1038/srep14629

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