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Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding
The polymerase chain reaction (PCR) is one of the most widely used techniques in molecular biology. In combination with High Throughput Sequencing (HTS), PCR is widely used to quantify transcript abundance for RNA-seq, and in the context of analysis of T and B cell receptor repertoires. In this stud...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602216/ https://www.ncbi.nlm.nih.gov/pubmed/26459131 http://dx.doi.org/10.1038/srep14629 |