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Gestational age and newborn size according to parental social mobility: an intergenerational cohort study
BACKGROUND: We examined the associations between socioeconomic trajectories from birth to adulthood and gestational age and birth size in the next generation, using linked data from two population-based birth cohorts carried out in a Brazilian city. By comparing socioeconomic trajectories of mothers...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602273/ https://www.ncbi.nlm.nih.gov/pubmed/26109560 http://dx.doi.org/10.1136/jech-2014-205377 |
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author | Gigante, Denise P Horta, Bernardo L Matijasevich, Alicia Loret de Mola, Christian Barros, Aluisio J D Santos, Ina S Barros, Fernando C Victora, Cesar G |
author_facet | Gigante, Denise P Horta, Bernardo L Matijasevich, Alicia Loret de Mola, Christian Barros, Aluisio J D Santos, Ina S Barros, Fernando C Victora, Cesar G |
author_sort | Gigante, Denise P |
collection | PubMed |
description | BACKGROUND: We examined the associations between socioeconomic trajectories from birth to adulthood and gestational age and birth size in the next generation, using linked data from two population-based birth cohorts carried out in a Brazilian city. By comparing socioeconomic trajectories of mothers and fathers, we attempted to identify-specific effects of maternal and paternal socioeconomic trajectory on offspring birth weight, birth length, head circumference and gestational age at birth. METHODS: 2 population-based birth cohort studies were carried out in 1982 and 2004 in Pelotas (Brazil); 156 mothers and 110 fathers from the earlier cohort had children in 2004. Gestational age and birth length, weight and head circumference were measured. Analyses were carried out separately for mothers and fathers. Mediation analyses assessed the role of birth weight and adult body mass index (BMI). RESULTS: Among mothers, but not for fathers, childhood poverty was strongly associated with smaller size in the next generation (about 400 g in weight and 1.5 cm in height) and shorter gestations (about 2 weeks). Adult poverty did not play a role. For mothers, the associations with gestational age, birth length and weight—but not with head circumference—persisted after adjusting for maternal birth weight and for the height and weight of the grandmother. Maternal birth weight did not mediate the observed associations, but high maternal BMI in adulthood was partly responsible for the association with gestational age. CONCLUSIONS: Strong effects of early poverty on gestational age and birth size in the next generation were observed among mothers, but not among fathers. These findings suggest a specific maternal effect of socioeconomic trajectory, and in particular of early poverty on offspring size and duration of pregnancy. |
format | Online Article Text |
id | pubmed-4602273 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-46022732015-10-21 Gestational age and newborn size according to parental social mobility: an intergenerational cohort study Gigante, Denise P Horta, Bernardo L Matijasevich, Alicia Loret de Mola, Christian Barros, Aluisio J D Santos, Ina S Barros, Fernando C Victora, Cesar G J Epidemiol Community Health Intergenerational Factors and Health BACKGROUND: We examined the associations between socioeconomic trajectories from birth to adulthood and gestational age and birth size in the next generation, using linked data from two population-based birth cohorts carried out in a Brazilian city. By comparing socioeconomic trajectories of mothers and fathers, we attempted to identify-specific effects of maternal and paternal socioeconomic trajectory on offspring birth weight, birth length, head circumference and gestational age at birth. METHODS: 2 population-based birth cohort studies were carried out in 1982 and 2004 in Pelotas (Brazil); 156 mothers and 110 fathers from the earlier cohort had children in 2004. Gestational age and birth length, weight and head circumference were measured. Analyses were carried out separately for mothers and fathers. Mediation analyses assessed the role of birth weight and adult body mass index (BMI). RESULTS: Among mothers, but not for fathers, childhood poverty was strongly associated with smaller size in the next generation (about 400 g in weight and 1.5 cm in height) and shorter gestations (about 2 weeks). Adult poverty did not play a role. For mothers, the associations with gestational age, birth length and weight—but not with head circumference—persisted after adjusting for maternal birth weight and for the height and weight of the grandmother. Maternal birth weight did not mediate the observed associations, but high maternal BMI in adulthood was partly responsible for the association with gestational age. CONCLUSIONS: Strong effects of early poverty on gestational age and birth size in the next generation were observed among mothers, but not among fathers. These findings suggest a specific maternal effect of socioeconomic trajectory, and in particular of early poverty on offspring size and duration of pregnancy. BMJ Publishing Group 2015-10 2015-06-24 /pmc/articles/PMC4602273/ /pubmed/26109560 http://dx.doi.org/10.1136/jech-2014-205377 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Intergenerational Factors and Health Gigante, Denise P Horta, Bernardo L Matijasevich, Alicia Loret de Mola, Christian Barros, Aluisio J D Santos, Ina S Barros, Fernando C Victora, Cesar G Gestational age and newborn size according to parental social mobility: an intergenerational cohort study |
title | Gestational age and newborn size according to parental social mobility: an intergenerational cohort study |
title_full | Gestational age and newborn size according to parental social mobility: an intergenerational cohort study |
title_fullStr | Gestational age and newborn size according to parental social mobility: an intergenerational cohort study |
title_full_unstemmed | Gestational age and newborn size according to parental social mobility: an intergenerational cohort study |
title_short | Gestational age and newborn size according to parental social mobility: an intergenerational cohort study |
title_sort | gestational age and newborn size according to parental social mobility: an intergenerational cohort study |
topic | Intergenerational Factors and Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602273/ https://www.ncbi.nlm.nih.gov/pubmed/26109560 http://dx.doi.org/10.1136/jech-2014-205377 |
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