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The coordination of unprotonated peptide tertiary structure as a metric of pMHC–TCR functional avidity

The coordination difference between the unprotonated tertiary structures of a native (Tax) peptide and a number of its variants – all peptides presented by HLA-A201 and bound to the human A6 T cell receptor-was discovered to constitute a metric of pMHC–TCR functional avidity. Moreover, increasing co...

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Detalles Bibliográficos
Autores principales: Antipas, Georgios S.E., Germenis, Anastasios E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602356/
https://www.ncbi.nlm.nih.gov/pubmed/26568977
http://dx.doi.org/10.1016/j.dib.2015.09.009