Cargando…
The coordination of unprotonated peptide tertiary structure as a metric of pMHC–TCR functional avidity
The coordination difference between the unprotonated tertiary structures of a native (Tax) peptide and a number of its variants – all peptides presented by HLA-A201 and bound to the human A6 T cell receptor-was discovered to constitute a metric of pMHC–TCR functional avidity. Moreover, increasing co...
Autores principales: | Antipas, Georgios S.E., Germenis, Anastasios E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602356/ https://www.ncbi.nlm.nih.gov/pubmed/26568977 http://dx.doi.org/10.1016/j.dib.2015.09.009 |
Ejemplares similares
-
The quantum chemical causality of pMHC-TCR biological avidity: Peptide atomic coordination data and the electronic state of agonist N termini
por: Antipas, Georgios S.E., et al.
Publicado: (2015) -
Human Cytomegalovirus variant peptides adapt by decreasing their total coordination upon binding to a T cell receptor
por: Antipas, Georgios S.E., et al.
Publicado: (2015) -
Atomic Coordination Reflects Peptide Immunogenicity
por: Antipas, Georgios S. E., et al.
Publicado: (2016) -
Identification and isolation of high avidity tumor-specific CD8 T cells by experimentally assessing pMHC-TCR binding parameters with soluble pMHC complexes
por: Schmidt, Julien, et al.
Publicado: (2015) -
Quantum chemical calculations predict biological function: the case of T cell receptor interaction with a peptide/MHC class I
por: Antipas, Georgios S. E., et al.
Publicado: (2015)