IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein

The interferon-induced transmembrane (IFITM) proteins have been recently shown to restrict HIV-1 and other viruses. Here, we provide evidence that IFITM proteins, particularly IFITM2 and IFITM3, specifically antagonize the HIV-1 envelope glycoprotein (Env), thereby inhibiting viral infection. IFITM...

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Detalles Bibliográficos
Autores principales: Yu, Jingyou, Li, Minghua, Wilkins, Jordan, Ding, Shilei, Swartz, Talia H., Esposito, Anthony M., Zheng, Yi-Min, Freed, Eric O., Liang, Chen, Chen, Benjamin K., Liu, Shan-Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602366/
https://www.ncbi.nlm.nih.gov/pubmed/26387945
http://dx.doi.org/10.1016/j.celrep.2015.08.055

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