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A chimeric human–mouse model of Sjögren's syndrome

Despite recent advances in the understanding of Sjögren's Syndrome (SjS), the pathogenic mechanisms remain elusive and an ideal model for early drug discovery is not yet available. To establish a humanized mouse model of SjS, peripheral blood mononuclear cells (PBMCs) from healthy volunteers or...

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Detalles Bibliográficos
Autores principales: Young, Nicholas A., Wu, Lai-Chu, Bruss, Michael, Kaffenberger, Benjamin H., Hampton, Jeffrey, Bolon, Brad, Jarjour, Wael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602403/
https://www.ncbi.nlm.nih.gov/pubmed/25451161
http://dx.doi.org/10.1016/j.clim.2014.10.004

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