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Adult Perithyroid and Cervical Thymus-Parathyroid Unit: Case Reports of a Rare Entity
The thymus-parathyroid unit (TPU) occurring in adults is rare. The main symptoms and important clinical findings are as follows: 2 patients presented with neomercazole-resistant Basedow–Graves disease. A third patient presented with thyroid nodules and a fourth patient with a neck mass after thyroid...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602809/ https://www.ncbi.nlm.nih.gov/pubmed/25501075 http://dx.doi.org/10.1097/MD.0000000000000201 |
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author | Handra-Luca, Adriana |
author_facet | Handra-Luca, Adriana |
author_sort | Handra-Luca, Adriana |
collection | PubMed |
description | The thymus-parathyroid unit (TPU) occurring in adults is rare. The main symptoms and important clinical findings are as follows: 2 patients presented with neomercazole-resistant Basedow–Graves disease. A third patient presented with thyroid nodules and a fourth patient with a neck mass after thyroid resection for medullary thyroid carcinoma. The main diagnoses were those of thyroid nodules (either in the context of goiter, or not). In the fourth case the diagnosis was of thyroid medullary carcinoma recurrence in the neck. Thyroidectomy was performed in the 2 cases of Basedow–Graves disease and in the third case (wherein selective neck dissection was also performed). In the fourth case, a neck dissection was performed for a possible medullary carcinoma recurrence. A TPU was microscopically detected in 2 cases with perithyroid location, on thyroidectomies for Basedow–Graves disease and in the 2 other cases with neck soft tissue location (associated with thyroid papillary carcinoma and thyroid medullary carcinoma extension). Postsurgical hypocalcemia requiring treatment occurred in both patients with Basedow–Graves disease and in the fourth patient. The presence of TPU should be acknowledged because such lesions can be misdiagnosed as suspect lymph nodes during thyroid surgery for malignant tumors. |
format | Online Article Text |
id | pubmed-4602809 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-46028092015-10-27 Adult Perithyroid and Cervical Thymus-Parathyroid Unit: Case Reports of a Rare Entity Handra-Luca, Adriana Medicine (Baltimore) 4100 The thymus-parathyroid unit (TPU) occurring in adults is rare. The main symptoms and important clinical findings are as follows: 2 patients presented with neomercazole-resistant Basedow–Graves disease. A third patient presented with thyroid nodules and a fourth patient with a neck mass after thyroid resection for medullary thyroid carcinoma. The main diagnoses were those of thyroid nodules (either in the context of goiter, or not). In the fourth case the diagnosis was of thyroid medullary carcinoma recurrence in the neck. Thyroidectomy was performed in the 2 cases of Basedow–Graves disease and in the third case (wherein selective neck dissection was also performed). In the fourth case, a neck dissection was performed for a possible medullary carcinoma recurrence. A TPU was microscopically detected in 2 cases with perithyroid location, on thyroidectomies for Basedow–Graves disease and in the 2 other cases with neck soft tissue location (associated with thyroid papillary carcinoma and thyroid medullary carcinoma extension). Postsurgical hypocalcemia requiring treatment occurred in both patients with Basedow–Graves disease and in the fourth patient. The presence of TPU should be acknowledged because such lesions can be misdiagnosed as suspect lymph nodes during thyroid surgery for malignant tumors. Wolters Kluwer Health 2014-12-12 /pmc/articles/PMC4602809/ /pubmed/25501075 http://dx.doi.org/10.1097/MD.0000000000000201 Text en Copyright © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | 4100 Handra-Luca, Adriana Adult Perithyroid and Cervical Thymus-Parathyroid Unit: Case Reports of a Rare Entity |
title | Adult Perithyroid and Cervical Thymus-Parathyroid Unit: Case Reports of a Rare Entity |
title_full | Adult Perithyroid and Cervical Thymus-Parathyroid Unit: Case Reports of a Rare Entity |
title_fullStr | Adult Perithyroid and Cervical Thymus-Parathyroid Unit: Case Reports of a Rare Entity |
title_full_unstemmed | Adult Perithyroid and Cervical Thymus-Parathyroid Unit: Case Reports of a Rare Entity |
title_short | Adult Perithyroid and Cervical Thymus-Parathyroid Unit: Case Reports of a Rare Entity |
title_sort | adult perithyroid and cervical thymus-parathyroid unit: case reports of a rare entity |
topic | 4100 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602809/ https://www.ncbi.nlm.nih.gov/pubmed/25501075 http://dx.doi.org/10.1097/MD.0000000000000201 |
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