Cardiac Protective Effects of Dexrazoxane on Animal Cardiotoxicity Model Induced by Anthracycline Combined With Trastuzumab Is Associated With Upregulation of Calpain-2

Cardiotoxicity is a well-recognized side effect induced by chemotherapeutic drugs such as anthracycline and trastuzumab through different mechanisms. Currently, accumulating evidence supports that dexrazoxane (DZR) can minimize the risk of cardiotoxicity. In this study, we investigated whether dexrz...

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Detalles Bibliográficos
Autores principales: Zhang, Sheng, Meng, Tingting, Liu, Jingjing, Zhang, Xiaobei, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
5700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602968/
https://www.ncbi.nlm.nih.gov/pubmed/25634181
http://dx.doi.org/10.1097/MD.0000000000000445

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