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Cord Blood-Derived Cytokine-Induced Killer Cellular Therapy Plus Radiation Therapy for Esophageal Cancer: A Case Report

Esophageal cancer is a serious malignancy with regards to mortality and prognosis. Current treatment options include multimodality therapy mainstays of current treatment including surgery, radiation, and chemotherapy. Cell therapy for esophageal cancer is an advancing area of research. We report a c...

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Autores principales: Wang, Liming, Huang, Shigao, Dang, Yazheng, Li, Ming, Bai, Wen, Zhong, Zhanqiang, Zhao, Hongliang, Li, Yang, Liu, Yongjun, Wu, Mingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603076/
https://www.ncbi.nlm.nih.gov/pubmed/25526496
http://dx.doi.org/10.1097/MD.0000000000000340
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author Wang, Liming
Huang, Shigao
Dang, Yazheng
Li, Ming
Bai, Wen
Zhong, Zhanqiang
Zhao, Hongliang
Li, Yang
Liu, Yongjun
Wu, Mingyuan
author_facet Wang, Liming
Huang, Shigao
Dang, Yazheng
Li, Ming
Bai, Wen
Zhong, Zhanqiang
Zhao, Hongliang
Li, Yang
Liu, Yongjun
Wu, Mingyuan
author_sort Wang, Liming
collection PubMed
description Esophageal cancer is a serious malignancy with regards to mortality and prognosis. Current treatment options include multimodality therapy mainstays of current treatment including surgery, radiation, and chemotherapy. Cell therapy for esophageal cancer is an advancing area of research. We report a case of esophageal cancer following cord blood-derived cytokine-induced killer cell infusion and adjuvant radiotherapy. Initially, she presented with poor spirit, full liquid diets, and upper abdominal pain. Through cell therapy plus adjuvant radiotherapy, the patient remitted and was self-reliant. Recognition of this curative effect of sequent therapy for esophageal cancer is important to enable appropriate treatment. This case highlights cord blood-derived cytokine-induced killer cell therapy significantly alleviates the adverse reaction of radiation and improves the curative effect. Cell therapy plus adjuvant radiotherapy can be a safe and effective treatment for esophageal cancer.
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spelling pubmed-46030762015-10-27 Cord Blood-Derived Cytokine-Induced Killer Cellular Therapy Plus Radiation Therapy for Esophageal Cancer: A Case Report Wang, Liming Huang, Shigao Dang, Yazheng Li, Ming Bai, Wen Zhong, Zhanqiang Zhao, Hongliang Li, Yang Liu, Yongjun Wu, Mingyuan Medicine (Baltimore) 5700 Esophageal cancer is a serious malignancy with regards to mortality and prognosis. Current treatment options include multimodality therapy mainstays of current treatment including surgery, radiation, and chemotherapy. Cell therapy for esophageal cancer is an advancing area of research. We report a case of esophageal cancer following cord blood-derived cytokine-induced killer cell infusion and adjuvant radiotherapy. Initially, she presented with poor spirit, full liquid diets, and upper abdominal pain. Through cell therapy plus adjuvant radiotherapy, the patient remitted and was self-reliant. Recognition of this curative effect of sequent therapy for esophageal cancer is important to enable appropriate treatment. This case highlights cord blood-derived cytokine-induced killer cell therapy significantly alleviates the adverse reaction of radiation and improves the curative effect. Cell therapy plus adjuvant radiotherapy can be a safe and effective treatment for esophageal cancer. Wolters Kluwer Health 2014-12-02 /pmc/articles/PMC4603076/ /pubmed/25526496 http://dx.doi.org/10.1097/MD.0000000000000340 Text en © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial License, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 5700
Wang, Liming
Huang, Shigao
Dang, Yazheng
Li, Ming
Bai, Wen
Zhong, Zhanqiang
Zhao, Hongliang
Li, Yang
Liu, Yongjun
Wu, Mingyuan
Cord Blood-Derived Cytokine-Induced Killer Cellular Therapy Plus Radiation Therapy for Esophageal Cancer: A Case Report
title Cord Blood-Derived Cytokine-Induced Killer Cellular Therapy Plus Radiation Therapy for Esophageal Cancer: A Case Report
title_full Cord Blood-Derived Cytokine-Induced Killer Cellular Therapy Plus Radiation Therapy for Esophageal Cancer: A Case Report
title_fullStr Cord Blood-Derived Cytokine-Induced Killer Cellular Therapy Plus Radiation Therapy for Esophageal Cancer: A Case Report
title_full_unstemmed Cord Blood-Derived Cytokine-Induced Killer Cellular Therapy Plus Radiation Therapy for Esophageal Cancer: A Case Report
title_short Cord Blood-Derived Cytokine-Induced Killer Cellular Therapy Plus Radiation Therapy for Esophageal Cancer: A Case Report
title_sort cord blood-derived cytokine-induced killer cellular therapy plus radiation therapy for esophageal cancer: a case report
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603076/
https://www.ncbi.nlm.nih.gov/pubmed/25526496
http://dx.doi.org/10.1097/MD.0000000000000340
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