Cargando…

The Role of Cytochromes P450 and Aldo-Keto Reductases in Prognosis of Breast Carcinoma Patients

Metabolism of anticancer drugs affects their antitumor effects. This study has investigated the associations of gene expression of enzymes metabolizing anticancer drugs with therapy response and survival of breast carcinoma patients. Gene expression of 13 aldo-keto reductases (AKRs), carbonyl reduct...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hlaváč, Viktor, Brynychová, Veronika, Václavíková, Radka, Ehrlichová, Marie, Vrána, David, Pecha, Václav, Trnková, Markéta, Kodet, Roman, Mrhalová, Marcela, Kubáčková, Kateřina, Gatěk, Jiří, Vážan, Petr, Souček, Pavel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2014
Materias:	5700
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603110/ https://www.ncbi.nlm.nih.gov/pubmed/25526449 http://dx.doi.org/10.1097/MD.0000000000000255

Ejemplares similares

Role of Genetic Variation in Cytochromes P450 in Breast Cancer Prognosis and Therapy Response
por: Hlaváč, Viktor, et al.
Publicado: (2021)

Non-Coding Polymorphisms in Nucleotide Binding Domain 1 in ABCC1 Gene Associate with Transcript Level and Survival of Patients with Breast Cancer
por: Kunická, Tereza, et al.
Publicado: (2014)

Role of Genetic Variation in ABC Transporters in Breast Cancer Prognosis and Therapy Response
por: Hlaváč, Viktor, et al.
Publicado: (2020)

Integrative analysis of mRNA and miRNA expression profiles and somatic variants in oxysterol signaling in early‐stage luminal breast cancer
por: Holý, Petr, et al.
Publicado: (2023)

Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients
por: Hlavac, Viktor, et al.
Publicado: (2018)

Prognostic value of aldo-keto reductase family 1 member B10 (AKR1B10) in digestive system cancers: A meta-analysis
por: Liu, Rongqiang, et al.
Publicado: (2021)

ABC Transporters and Their Role in the Neoadjuvant Treatment of Esophageal Cancer
por: Vrana, David, et al.
Publicado: (2018)

Aldo-Keto Reductases in the Eye
por: Huang, Shun Ping, et al.
Publicado: (2010)

Whole-exome sequencing of epithelial ovarian carcinomas differing in resistance to platinum therapy
por: Hlaváč, Viktor, et al.
Publicado: (2022)

Regulation of Aldo–Keto Reductases in Human Diseases
por: Chen, Wei-Dong, et al.
Publicado: (2012)

Pharmacogenomics to Predict Tumor Therapy Response: A Focus on ATP-Binding Cassette Transporters and Cytochromes P450
por: Hlaváč, Viktor, et al.
Publicado: (2020)

Aldo-keto reductase (AKR) superfamily: Genomics and annotation
por: Mindnich, Rebekka D, et al.
Publicado: (2009)

Aldo-Keto Reductases 1B in Endocrinology and Metabolism
por: Pastel, Emilie, et al.
Publicado: (2012)

Acceleration of an aldo-keto reductase by minimal loop engineering
por: Krump, C., et al.
Publicado: (2014)

Cytochrome P450 1A1 gene polymorphisms and cervical cancer risk: A systematic review and meta-analysis
por: Ding, Bo, et al.
Publicado: (2018)

Semi-rational engineering an aldo–keto reductase for stereocomplementary reduction of α-keto amide compounds
por: Bai, Ruixuan, et al.
Publicado: (2023)

Role of Aldo–Keto Reductase Enzymes in Mediating the Timing of Parturition
por: Byrns, Michael C.
Publicado: (2012)

Aldo-Keto Reductases 1B in Adrenal Cortex Physiology
por: Pastel, Emilie, et al.
Publicado: (2016)

Biological Role of Aldo–Keto Reductases in Retinoic Acid Biosynthesis and Signaling
por: Ruiz, F. Xavier, et al.
Publicado: (2012)

Editorial on research topic: aldo-keto reductases and role in human disease
por: Jin, Yi
Publicado: (2013)

Human Aldo-Keto Reductases and the Metabolic Activation of Polycyclic Aromatic Hydrocarbons
por: Penning, Trevor M.
Publicado: (2014)

The Coptotermes gestroi aldo–keto reductase: a multipurpose enzyme for biorefinery applications
por: Tramontina, Robson, et al.
Publicado: (2017)

A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism
por: Roberts, Adam J., et al.
Publicado: (2018)

Aldo‐keto reductase enzymes detoxify glyphosate and improve herbicide resistance in plants
por: Vemanna, Ramu S., et al.
Publicado: (2017)

Regulation of Gluconeogenesis by Aldo-keto-reductase 1a1b in Zebrafish
por: Li, Xiaogang, et al.
Publicado: (2020)

Structure–function characterization of an aldo–keto reductase involved in detoxification of the mycotoxin, deoxynivalenol
por: Abraham, Nadine, et al.
Publicado: (2022)

New Insights into the Role of the Trypanosoma cruzi Aldo-Keto Reductase TcAKR
por: Díaz-Viraqué, Florencia, et al.
Publicado: (2023)

The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes
por: Seborova, Karolina, et al.
Publicado: (2021)

Quantitative Evaluation of Aldo–keto Reductase Expression in Hepatocellular Carcinoma (HCC) Cell Lines
por: Yang, Lei, et al.
Publicado: (2013)

Effects of ligand binding on the stability of aldo–keto reductases: Implications for stabilizer or destabilizer chaperones
por: Kabir, Aurangazeb, et al.
Publicado: (2016)

Aldo‐keto reductases‐mediated cytotoxicity of 2‐deoxyglucose: A novel anticancer mechanism
por: Zhang, Shi‐Qing, et al.
Publicado: (2018)

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis
por: Gagliardi, Mara, et al.
Publicado: (2019)

Perspective on the Structural Basis for Human Aldo-Keto Reductase 1B10 Inhibition
por: Ruiz, Francesc Xavier, et al.
Publicado: (2021)

Michaelis-Menten Kinetics Measurements of Aldo-Keto Reductases for Various Substrates in Murine Tissue
por: Morgenstern, Jakob, et al.
Publicado: (2020)

Aldo-Keto Reductase 1C15 Characterization and Protection in Ischemic Brain Injury
por: Yang, Tuo, et al.
Publicado: (2023)

Babesia microti Aldo-keto Reductase-Like Protein Involved in Antioxidant and Anti-parasite Response
por: Huang, Qiang, et al.
Publicado: (2017)

An aldo-keto reductase is responsible for Fusarium toxin-degrading activity in a soil Sphingomonas strain
por: He, Wei-Jie, et al.
Publicado: (2017)

Regulation Network and Prognostic Significance of Aldo-Keto Reductase (AKR) Superfamily Genes in Hepatocellular Carcinoma
por: Dai, Tianxing, et al.
Publicado: (2021)

Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases
por: Detlefsen, Andrea J., et al.
Publicado: (2023)

The Specific Binding and Promotion Effect of Azoles on Human Aldo-Keto Reductase 7A2
por: Wu, Wanying, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8ls7ts59hjv7qnivoqfcgnuoh7