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Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype
BACKGROUND: The CpG island methylator phenotype (CIMP) was first characterized in colorectal cancer but since has been extensively studied in several other tumor types such as breast, bladder, lung, and gastric. CIMP is of clinical importance as it has been reported to be associated with prognosis o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603341/ https://www.ncbi.nlm.nih.gov/pubmed/26463173 http://dx.doi.org/10.1186/s40246-015-0048-9 |