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Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype

BACKGROUND: The CpG island methylator phenotype (CIMP) was first characterized in colorectal cancer but since has been extensively studied in several other tumor types such as breast, bladder, lung, and gastric. CIMP is of clinical importance as it has been reported to be associated with prognosis o...

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Detalles Bibliográficos
Autores principales: Moarii, Matahi, Reyal, Fabien, Vert, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603341/
https://www.ncbi.nlm.nih.gov/pubmed/26463173
http://dx.doi.org/10.1186/s40246-015-0048-9