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Dimethyl fumarate inhibits integrin α4 expression in multiple sclerosis models

Dimethyl fumarate is an orally bioavailable compound for the treatment of multiple sclerosis and psoriasis. A mechanism involving nuclear factor erythroid 2-like 2 activation has been proposed to account for its efficacy in multiple sclerosis. Here, we report that dimethyl fumarate inhibits expressi...

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Detalles Bibliográficos
Autores principales: Kihara, Yasuyuki, Groves, Aran, Rivera, Richard R, Chun, Jerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603381/
https://www.ncbi.nlm.nih.gov/pubmed/26478898
http://dx.doi.org/10.1002/acn3.251

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