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Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives

Due to the topological effect, cyclic polymers demonstrate different and unique physical and biological properties in comparison with linear counterparts having the same molecular-weight range. With advanced synthetic and analytic technologies, cyclic polymers with different topologies, e.g. multicy...

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Detalles Bibliográficos
Autores principales: Zhu, Yinghuai, Hosmane, Narayan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603400/
https://www.ncbi.nlm.nih.gov/pubmed/26478835
http://dx.doi.org/10.1002/open.201402172
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author Zhu, Yinghuai
Hosmane, Narayan S
author_facet Zhu, Yinghuai
Hosmane, Narayan S
author_sort Zhu, Yinghuai
collection PubMed
description Due to the topological effect, cyclic polymers demonstrate different and unique physical and biological properties in comparison with linear counterparts having the same molecular-weight range. With advanced synthetic and analytic technologies, cyclic polymers with different topologies, e.g. multicyclic polymers, have been reported and well characterized. For example, various cyclic DNA and related structures, such as cyclic duplexes, have been prepared conveniently by click chemistry. These types of DNA have increased resistance to enzymatic degradation and have high thermodynamic stability, and thus, have potential therapeutic applications. In addition, cyclic polymers have also been used to prepare organic–inorganic hybrids for applications in catalysis, e.g. catalyst supports. Due to developments in synthetic technology, highly pure cyclic polymers could now be produced in large scale. Therefore, we anticipate discovering more applications in the near future. Despite their promise, cyclic polymers are still less explored than linear polymers like polyolefins and polycarbonates, which are widely used in daily life. Some critical issues, including controlling the molecular weight and finding suitable applications, remain big challenges in the cyclic-polymer field. This review briefly summarizes the commonly used synthetic methodologies and focuses more on the attractive functional materials and their biological properties and potential applications.
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spelling pubmed-46034002015-10-16 Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives Zhu, Yinghuai Hosmane, Narayan S ChemistryOpen Reviews Due to the topological effect, cyclic polymers demonstrate different and unique physical and biological properties in comparison with linear counterparts having the same molecular-weight range. With advanced synthetic and analytic technologies, cyclic polymers with different topologies, e.g. multicyclic polymers, have been reported and well characterized. For example, various cyclic DNA and related structures, such as cyclic duplexes, have been prepared conveniently by click chemistry. These types of DNA have increased resistance to enzymatic degradation and have high thermodynamic stability, and thus, have potential therapeutic applications. In addition, cyclic polymers have also been used to prepare organic–inorganic hybrids for applications in catalysis, e.g. catalyst supports. Due to developments in synthetic technology, highly pure cyclic polymers could now be produced in large scale. Therefore, we anticipate discovering more applications in the near future. Despite their promise, cyclic polymers are still less explored than linear polymers like polyolefins and polycarbonates, which are widely used in daily life. Some critical issues, including controlling the molecular weight and finding suitable applications, remain big challenges in the cyclic-polymer field. This review briefly summarizes the commonly used synthetic methodologies and focuses more on the attractive functional materials and their biological properties and potential applications. John Wiley & Sons, Ltd 2015-08 2015-05-29 /pmc/articles/PMC4603400/ /pubmed/26478835 http://dx.doi.org/10.1002/open.201402172 Text en © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Reviews
Zhu, Yinghuai
Hosmane, Narayan S
Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives
title Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives
title_full Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives
title_fullStr Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives
title_full_unstemmed Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives
title_short Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives
title_sort advanced developments in cyclic polymers: synthesis, applications, and perspectives
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603400/
https://www.ncbi.nlm.nih.gov/pubmed/26478835
http://dx.doi.org/10.1002/open.201402172
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