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Tetra- versus Pentavalent Inhibitors of Cholera Toxin**

The five B-subunits (CTB(5)) of the Vibrio cholerae (cholera) toxin can bind to the intestinal cell surface so the entire AB(5) toxin can enter the cell. Simultaneous binding can occur on more than one of the monosialotetrahexosylganglioside (GM1) units present on the cell surface. Such simultaneous...

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Detalles Bibliográficos
Autores principales: Fu, Ou, Pukin, Aliaksei V, van Ufford, H C Quarles, Branson, Thomas R, Thies-Weesie, Dominique M E, Turnbull, W Bruce, Visser, Gerben M, Pieters, Roland J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603408/
https://www.ncbi.nlm.nih.gov/pubmed/26478842
http://dx.doi.org/10.1002/open.201500006