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Tetra- versus Pentavalent Inhibitors of Cholera Toxin**
The five B-subunits (CTB(5)) of the Vibrio cholerae (cholera) toxin can bind to the intestinal cell surface so the entire AB(5) toxin can enter the cell. Simultaneous binding can occur on more than one of the monosialotetrahexosylganglioside (GM1) units present on the cell surface. Such simultaneous...
Autores principales: | Fu, Ou, Pukin, Aliaksei V, van Ufford, H C Quarles, Branson, Thomas R, Thies-Weesie, Dominique M E, Turnbull, W Bruce, Visser, Gerben M, Pieters, Roland J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603408/ https://www.ncbi.nlm.nih.gov/pubmed/26478842 http://dx.doi.org/10.1002/open.201500006 |
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