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Proteomic analysis of extracellular vesicles from medullospheres reveals a role for iron in the cancer progression of medulloblastoma

BACKGROUND: Medulloblastoma (MB) is the most common malignant childhood brain tumor with the propensity to disseminate at an early stage, and is associated with high morbidity. New treatment strategies are needed to improve cure rates and to reduce life-long cognitive and functional deficits associa...

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Detalles Bibliográficos
Autores principales: Bisaro, Brigitte, Mandili, Giorgia, Poli, Alice, Piolatto, Andrea, Papa, Valentina, Novelli, Francesco, Cenacchi, Giovanna, Forni, Marco, Zanini, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603768/
https://www.ncbi.nlm.nih.gov/pubmed/26464805
http://dx.doi.org/10.1186/s40591-015-0045-3

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