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Varied Probability of Staying Collapsed/Extended at the Conformational Equilibrium of Monomeric Aβ(40) and Aβ(42)
In present study, we set out to investigate the conformation dynamics of Aβ(40) and Aβ(42) through exploring the impact of intra-molecular interactions on conformation dynamics using equilibrium molecular dynamics simulations. Our 40 microsecond-scale simulations reveal heterogeneous conformation en...
Autores principales: | Song, Wanling, Wang, Yuanyuan, Colletier, Jacques-Philippe, Yang, Huaiyu, Xu, Yechun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603783/ https://www.ncbi.nlm.nih.gov/pubmed/26046578 http://dx.doi.org/10.1038/srep11024 |
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