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ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells

INTRODUCTION: Bone marrow-derived stromal cells (BMSCs), also known as mesenchymal stem cells, are the focus of intensive efforts worldwide to elucidate their function and biology. Despite the importance of BMSC migration for their potential therapeutic uses, the mechanisms and signalling governing...

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Detalles Bibliográficos
Autores principales: Ryan, Caroline M., Brown, James A. L., Bourke, Emer, Prendergast, Áine M., Kavanagh, Claire, Liu, Zhonglin, Owens, Peter, Shaw, Georgina, Kolch, Walter, O’Brien, Timothy, Barry, Frank P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603944/
https://www.ncbi.nlm.nih.gov/pubmed/26204937
http://dx.doi.org/10.1186/s13287-015-0125-y