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Role of Runx2 Phosphorylation in Prostate Cancer and Association with Metastatic Disease

The osteogenic transcription factor, Runx2, is abnormally expressed in prostate cancer (PCa) and associated with metastatic disease. During bone development, Runx2 is activated by signals known to be hyperactive in PCa including the RAS/MAP kinase pathway, which phosphorylates Runx2 on multiple seri...

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Detalles Bibliográficos
Autores principales:	Ge, Chunxi, Zhao, Guisheng, Li, Yan, Li, Hui, Zhao, Xiang, Pannone, Giuseppe, Bufo, Pantaleo, Santoro, Angela, Sanguedolce, Francesca, Tortorella, Simona, Mattoni, Marilena, Papagerakis, Silvana, Keller, Evan T., Franceschi, Renny T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603996/ https://www.ncbi.nlm.nih.gov/pubmed/25867060 http://dx.doi.org/10.1038/onc.2015.91

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