P2RX7 Purinoceptor: A Therapeutic Target for Ameliorating the Symptoms of Duchenne Muscular Dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is the most common inherited muscle disease, leading to severe disability and death in young men. Death is caused by the progressive degeneration of striated muscles aggravated by sterile inflammation. The pleiotropic effects of the mutant gene also incl...

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Detalles Bibliográficos
Autores principales: Sinadinos, Anthony, Young, Christopher N. J., Al-Khalidi, Rasha, Teti, Anna, Kalinski, Paweł, Mohamad, Shafini, Floriot, Léonore, Henry, Tiphaine, Tozzi, Gianluca, Jiang, Taiwen, Wurtz, Olivier, Lefebvre, Alexis, Shugay, Mikhail, Tong, Jie, Vaudry, David, Arkle, Stephen, doRego, Jean-Claude, Górecki, Dariusz C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604078/
https://www.ncbi.nlm.nih.gov/pubmed/26461208
http://dx.doi.org/10.1371/journal.pmed.1001888

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