Cargando…
Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome
To date, mitochondrial DNA polymerase γ (POLG) is the only polymerase known to be present in mammalian mitochondria. A dogma in the mitochondria field is that there is no other polymerase present in the mitochondria of mammalian cells. Here we demonstrate localization of REV3 DNA polymerase in the m...
Autores principales: | Singh, Bhupendra, Li, Xiurong, Owens, Kjerstin M., Vanniarajan, Ayyasamy, Liang, Ping, Singh, Keshav K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604079/ https://www.ncbi.nlm.nih.gov/pubmed/26462070 http://dx.doi.org/10.1371/journal.pone.0140409 |
Ejemplares similares
-
Mutations in mitochondrial DNA polymerase γ promote breast tumorigenesis
por: Singh, Keshav K., et al.
Publicado: (2009) -
Impaired OXPHOS Complex III in Breast Cancer
por: Owens, Kjerstin M., et al.
Publicado: (2011) -
Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties
por: Singh, Bhupendra, et al.
Publicado: (2015) -
p53 regulates mtDNA copy number and mitocheckpoint pathway
por: Kulawiec, Mariola, et al.
Publicado: (2009) -
Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin
por: Ayyasamy, Vanniarajan, et al.
Publicado: (2011)