Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells

BACKGROUND: Compromised colonic butyrate production resulting from low dietary fiber or altered gut microbiota may promote colon neoplasia. Previous reports indicate these actions are mediated in part by altered levels of miRNAs, including suppressed expression of the oncogenic miR-17-92a cluster. H...

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Detalles Bibliográficos
Autores principales: Hu, Shien, Liu, Lan, Chang, Eugene B., Wang, Jian-Ying, Raufman, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604099/
https://www.ncbi.nlm.nih.gov/pubmed/26463716
http://dx.doi.org/10.1186/s12943-015-0450-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604099/
https://www.ncbi.nlm.nih.gov/pubmed/26463716
http://dx.doi.org/10.1186/s12943-015-0450-x

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