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Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing
Here, we present evidence for a specific role of the splicing-related factor TCERG1 in regulating apoptosis in live cells by modulating the alternative splicing of the apoptotic genes Bcl-x and Fas. We show that TCERG1 modulates Bcl-x alternative splicing during apoptosis and its activity in Bcl-x a...
Autores principales: | Montes, Marta, Coiras, Mayte, Becerra, Soraya, Moreno-Castro, Cristina, Mateos, Elena, Majuelos, Jara, Oliver, F. Javier, Hernández-Munain, Cristina, Alcamí, José, Suñé, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604205/ https://www.ncbi.nlm.nih.gov/pubmed/26462236 http://dx.doi.org/10.1371/journal.pone.0139812 |
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