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Aneuploidy-induced cellular stresses limit autophagic degradation

An unbalanced karyotype, a condition known as aneuploidy, has a profound impact on cellular physiology and is a hallmark of cancer. Aneuploid cells experience a number of stresses that are caused by aneuploidy-induced proteomic changes. How the aneuploidy-associated stresses affect cells and whether...

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Detalles Bibliográficos
Autores principales: Santaguida, Stefano, Vasile, Eliza, White, Eileen, Amon, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604343/
https://www.ncbi.nlm.nih.gov/pubmed/26404941
http://dx.doi.org/10.1101/gad.269118.115

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