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Coevolution of RtcB and Archease created a multiple-turnover RNA ligase

RtcB is a noncanonical RNA ligase that joins either 2′,3′-cyclic phosphate or 3′-phosphate termini to 5′-hydroxyl termini. The genes encoding RtcB and Archease constitute a tRNA splicing operon in many organisms. Archease is a cofactor of RtcB that accelerates RNA ligation and alters the NTP specifi...

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Detalles Bibliográficos
Autores principales:	Desai, Kevin K., Beltrame, Amanda L., Raines, Ronald T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604427/ https://www.ncbi.nlm.nih.gov/pubmed/26385509 http://dx.doi.org/10.1261/rna.052639.115

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