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Splicing promotes the nuclear export of β-globin mRNA by overcoming nuclear retention elements

Most current models of mRNA nuclear export in vertebrate cells assume that an mRNA must have specialized signals in order to be exported from the nucleus. Under such a scenario, mRNAs that lack these specialized signals would be shunted into a default pathway where they are retained in the nucleus a...

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Detalles Bibliográficos
Autores principales: Akef, Abdalla, Lee, Eliza S., Palazzo, Alexander F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604431/
https://www.ncbi.nlm.nih.gov/pubmed/26362019
http://dx.doi.org/10.1261/rna.051987.115