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Splicing promotes the nuclear export of β-globin mRNA by overcoming nuclear retention elements
Most current models of mRNA nuclear export in vertebrate cells assume that an mRNA must have specialized signals in order to be exported from the nucleus. Under such a scenario, mRNAs that lack these specialized signals would be shunted into a default pathway where they are retained in the nucleus a...
Autores principales: | Akef, Abdalla, Lee, Eliza S., Palazzo, Alexander F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604431/ https://www.ncbi.nlm.nih.gov/pubmed/26362019 http://dx.doi.org/10.1261/rna.051987.115 |
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