E2 superfamily of ubiquitin-conjugating enzymes: constitutively active or activated through phosphorylation in the catalytic cleft

Protein phosphorylation is a modification that offers a dynamic and reversible mechanism to regulate the majority of cellular processes. Numerous diseases are associated with aberrant regulation of phosphorylation-induced switches. Phosphorylation is emerging as a mechanism to modulate ubiquitinatio...

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Detalles Bibliográficos
Autores principales: Valimberti, Ilaria, Tiberti, Matteo, Lambrughi, Matteo, Sarcevic, Boris, Papaleo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604453/
https://www.ncbi.nlm.nih.gov/pubmed/26463729
http://dx.doi.org/10.1038/srep14849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604453/
https://www.ncbi.nlm.nih.gov/pubmed/26463729
http://dx.doi.org/10.1038/srep14849

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