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In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging

Mutational acquired resistance is a major challenge in cancer therapy. Somatic tumours harbouring some oncogenic mutations are characterised by a high mortality rate. Surprisingly, preclinical evaluation methods do not show clearly resistance of mutated cancers to some drugs. Here, we implemented Ra...

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Detalles Bibliográficos
Autores principales: Yosef, Hesham K., Mavarani, Laven, Maghnouj, Abdelouahid, Hahn, Stephan, El-Mashtoly, Samir F., Gerwert, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604500/
https://www.ncbi.nlm.nih.gov/pubmed/26168967
http://dx.doi.org/10.1007/s00216-015-8875-z