Converging or Crossing Curves: Untie the Gordian Knot or Cut it? Appropriate Statistics for Non-Proportional Hazards in Decitabine DACO-016 Study (AML)

INTRODUCTION: Among patients with acute myeloid leukemia (AML), the DACO-016 randomized study showed reduction in mortality for decitabine [Dacogen(®) (DAC), Eisai Inc., Woodcliff Lake, NJ, USA] compared with treatment choice (TC): at primary analysis the hazard ratio (HR) was 0.85 (95% confidence i...

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Detalles Bibliográficos
Autores principales: Tomeczkowski, Jörg, Lange, Ansgar, Güntert, Andreas, Thilakarathne, Pushpike, Diels, Joris, Xiu, Liang, De Porre, Peter, Tapprich, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604504/
https://www.ncbi.nlm.nih.gov/pubmed/26369324
http://dx.doi.org/10.1007/s12325-015-0238-9

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