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An internal pilot design for prospective cancer screening trials with unknown disease prevalence
BACKGROUND: For studies that compare the diagnostic accuracy of two screening tests, the sample size depends on the prevalence of disease in the study population, and on the variance of the outcome. Both parameters may be unknown during the design stage, which makes finding an accurate sample size d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604650/ https://www.ncbi.nlm.nih.gov/pubmed/26463684 http://dx.doi.org/10.1186/s13063-015-0951-3 |