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Semaphorin-3C signals through Neuropilin-1 and PlexinD1 receptors to inhibit pathological angiogenesis

Retinopathy of prematurity causes visual impairment due to destructive neoangiogenesis after degeneration of the retinal microvasculature. This study was aimed at analyzing whether local delivery of Semaphorin-3C (Sema3C) suppresses pathological retinal angiogenesis. Sema3C exerted potent inhibiting...

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Detalles Bibliográficos
Autores principales: Yang, Wan-Jen, Hu, Junhao, Uemura, Akiyoshi, Tetzlaff, Fabian, Augustin, Hellmut G, Fischer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604683/
https://www.ncbi.nlm.nih.gov/pubmed/26194913
http://dx.doi.org/10.15252/emmm.201404922

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