High glucose induces and activates Toll-like receptor 4 in endothelial cells of diabetic retinopathy

BACKGROUND: Hyperglycemia-induced inflammation causes the dysfunction of blood vessels, and Toll-like receptor 4 (TLR4) plays a key role in inflammation-induced angiogenesis. However, the impact of TLR4 on the pathogenesis of diabetic retinopathy (DR) is poorly understood. In this study, we examined...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Wang, Jing, Fang, Jiazhu, Zhou, Hongyan, Liu, Xialin, Su, Shao Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604707/
https://www.ncbi.nlm.nih.gov/pubmed/26468333
http://dx.doi.org/10.1186/s13098-015-0086-4

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