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High PHLPP expression is associated with better prognosis in patients with resected lung adenocarcinoma

BACKGROUND: PH domain Leucine-rich-repeats protein phosphatase (PHLPP) is a novel family of Ser/Thr protein dephosphatases that play a critical role in maintaining the balance in cell signaling. PHLPP negatively regulates PI3K/Akt and RAF/RAS/′ signaling activation, which is crucial in development,...

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Detalles Bibliográficos
Autores principales:	Lv, Dongqing, Yang, Haihua, Wang, Wei, Xie, Youyou, Hu, Wei, Ye, Minhua, Chen, Xiaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604720/ https://www.ncbi.nlm.nih.gov/pubmed/26463718 http://dx.doi.org/10.1186/s12885-015-1711-1

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