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Development of a new model system to dissect isoform specific Akt signalling in adipocytes

Protein kinase B (Akt) kinases are critical signal transducers mediating insulin action. Genetic studies revealed that Akt1 and Akt2 signalling differentially contribute to sustain lipid and glucose homoeostasis; however Akt isoform-specific effectors remain elusive due to the lack of a suitable mod...

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Detalles Bibliográficos
Autores principales:	Kajno, Esi, McGraw, Timothy E., Gonzalez, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604748/ https://www.ncbi.nlm.nih.gov/pubmed/25856301 http://dx.doi.org/10.1042/BJ20150191

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