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T Lymphocyte Inhibition by Tumor-Infiltrating Dendritic Cells Involves Ectonucleotidase CD39 but Not Arginase-1
T lymphocytes activated by dendritic cells (DC) which present tumor antigens play a key role in the antitumor immune response. However, in patients suffering from active cancer, DC are not efficient at initiating and supporting immune responses as they participate to T lymphocyte inhibition. DC in t...
Autores principales: | Trad, Malika, Gautheron, Alexandrine, Fraszczak, Jennifer, Alizadeh, Darya, Larmonier, Claire, LaCasse, Collin J., Centuori, Sara, Audia, Sylvain, Samson, Maxime, Ciudad, Marion, Bonnefoy, Francis, Lemaire-Ewing, Stéphanie, Katsanis, Emmanuel, Perruche, Sylvain, Saas, Philippe, Bonnotte, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605267/ https://www.ncbi.nlm.nih.gov/pubmed/26491691 http://dx.doi.org/10.1155/2015/891236 |
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