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Cas9-chromatin binding information enables more accurate CRISPR off-target prediction
The CRISPR system has become a powerful biological tool with a wide range of applications. However, improving targeting specificity and accurately predicting potential off-targets remains a significant goal. Here, we introduce a web-based CRISPR/Cas9 Off-target Prediction and Identification Tool (CR...
Autores principales: | Singh, Ritambhara, Kuscu, Cem, Quinlan, Aaron, Qi, Yanjun, Adli, Mazhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605288/ https://www.ncbi.nlm.nih.gov/pubmed/26032770 http://dx.doi.org/10.1093/nar/gkv575 |
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