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Varying levels of complexity in transcription factor binding motifs

Binding of transcription factors to DNA is one of the keystones of gene regulation. The existence of statistical dependencies between binding site positions is widely accepted, while their relevance for computational predictions has been debated. Building probabilistic models of binding sites that m...

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Detalles Bibliográficos
Autores principales: Keilwagen, Jens, Grau, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605289/
https://www.ncbi.nlm.nih.gov/pubmed/26116565
http://dx.doi.org/10.1093/nar/gkv577