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A predictive modeling approach for cell line-specific long-range regulatory interactions

Long range regulatory interactions among distal enhancers and target genes are important for tissue-specific gene expression. Genome-scale identification of these interactions in a cell line-specific manner, especially using the fewest possible datasets, is a significant challenge. We develop a nove...

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Detalles Bibliográficos
Autores principales: Roy, Sushmita, Siahpirani, Alireza Fotuhi, Chasman, Deborah, Knaack, Sara, Ay, Ferhat, Stewart, Ron, Wilson, Michael, Sridharan, Rupa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605315/
https://www.ncbi.nlm.nih.gov/pubmed/26338778
http://dx.doi.org/10.1093/nar/gkv865

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