ATP dependent NS3 helicase interaction with RNA: insights from molecular simulations

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Non-structural protein 3 (NS3) helicase from hepatitis C virus is an enzyme that unwinds and translocates along nucleic acids with an ATP-dependent mechanism and has a key role in the replication of the viral RNA. An inchworm-like mechanism for translocation has been proposed based on crystal struct...

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Detalles Bibliográficos
Autores principales: Pérez-Villa, Andrea, Darvas, Maria, Bussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605317/
https://www.ncbi.nlm.nih.gov/pubmed/26358809
http://dx.doi.org/10.1093/nar/gkv872

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