Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction

Strategies to limit damage and improve repair after myocardial infarct remain a major therapeutic goal in cardiology. Our previous studies have shown that constitutive expression of a locally acting insulin-like growth factor-1 Ea (IGF-1Ea) propeptide promotes functional restoration after cardiac in...

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Detalles Bibliográficos
Autores principales: Gallego-Colon, Enrique, Sampson, Robert D., Sattler, Susanne, Schneider, Michael D., Rosenthal, Nadia, Tonkin, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605352/
https://www.ncbi.nlm.nih.gov/pubmed/26491228
http://dx.doi.org/10.1155/2015/484357

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