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Optimisation of a micro-neutralisation assay and its application in antigenic characterisation of influenza viruses

OBJECTIVES: The identification of antigenic variants and the selection of influenza viruses for vaccine production are based largely on antigenic characterisation of the haemagglutinin (HA) of circulating viruses using the haemagglutination inhibition (HI) assay. However, in addition to evolution re...

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Detalles Bibliográficos
Autores principales: Lin, Yipu, Gu, Yan, Wharton, Stephen A, Whittaker, Lynne, Gregory, Victoria, Li, Xiaoyan, Metin, Simon, Cattle, Nicholas, Daniels, Rodney S, Hay, Alan J, McCauley, John W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605415/
https://www.ncbi.nlm.nih.gov/pubmed/26073976
http://dx.doi.org/10.1111/irv.12333