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A Cilia Independent Role of Ift88/Polaris during Cell Migration

Ift88 is a central component of the intraflagellar transport (Ift) complex B, essential for the building of cilia and flagella from single cell organisms to mammals. Loss of Ift88 results in the absence of cilia and causes left-right asymmetry defects, disordered Hedgehog signaling, and polycystic k...

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Detalles Bibliográficos
Autores principales: Boehlke, Christopher, Janusch, Heike, Hamann, Christoph, Powelske, Christian, Mergen, Miriam, Herbst, Henriette, Kotsis, Fruzsina, Nitschke, Roland, Kuehn, E. Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605505/
https://www.ncbi.nlm.nih.gov/pubmed/26465598
http://dx.doi.org/10.1371/journal.pone.0140378

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