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Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres

The uncapping of telomeres induces a DNA damage response. In Schizosaccharomyces pombe, deletion of pot1 (+) causes telomere uncapping and rapid telomere resection, resulting in chromosome fusion. Using the nmt-pot1-aid strain, we previously reported that Pot1 shut-off causes telomere loss and chrom...

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Detalles Bibliográficos
Autores principales: Nanbu, Tomoko, Nguyễn, Luân C., Habib, Ahmed G. K., Hirata, Naoya, Ukimori, Shinobu, Tanaka, Daiki, Masuda, Kenta, Takahashi, Katsunori, Yukawa, Masashi, Tsuchiya, Eiko, Ueno, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605587/
https://www.ncbi.nlm.nih.gov/pubmed/26465752
http://dx.doi.org/10.1371/journal.pone.0140456