Cargando…
Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres
The uncapping of telomeres induces a DNA damage response. In Schizosaccharomyces pombe, deletion of pot1 (+) causes telomere uncapping and rapid telomere resection, resulting in chromosome fusion. Using the nmt-pot1-aid strain, we previously reported that Pot1 shut-off causes telomere loss and chrom...
Autores principales: | Nanbu, Tomoko, Nguyễn, Luân C., Habib, Ahmed G. K., Hirata, Naoya, Ukimori, Shinobu, Tanaka, Daiki, Masuda, Kenta, Takahashi, Katsunori, Yukawa, Masashi, Tsuchiya, Eiko, Ueno, Masaru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605587/ https://www.ncbi.nlm.nih.gov/pubmed/26465752 http://dx.doi.org/10.1371/journal.pone.0140456 |
Ejemplares similares
-
Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1
por: Tsolou, Avgi, et al.
Publicado: (2007) -
Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping
por: Dewar, James M, et al.
Publicado: (2010) -
Multiple roles for Mre11 at uncapped telomeres
por: Deng, Yibin, et al.
Publicado: (2009) -
Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine
por: Shamim, Hossain Mohammad, et al.
Publicado: (2017) -
Uncapping and Deregulation of Telomeres Lead to Detrimental Cellular Consequences in Yeast
por: Smith, Christopher D., et al.
Publicado: (1999)