Src Tyrosine Kinase Activation by 4-Hydroxynonenal Upregulates p38, ERK/AP-1 Signaling and COX-2 Expression in YPEN-1 Cells

4-Hydroxynonenal (4-HNE), a major end product of lipid peroxidation, is highly reactive and involved in various cellular processes, such as inflammatory signaling. However, to date, the mechanistic roles of 4-HNE in inflammatory signaling related to protein tyrosine kinases have not been elucidated....

Descripción completa

Detalles Bibliográficos
Autores principales: Jang, Eun Ji, Jeong, Hyoung Oh, Park, Daeui, Kim, Dae Hyun, Choi, Yeon Ja, Chung, Ki Wung, Park, Min Hi, Yu, Byung Pal, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605600/
https://www.ncbi.nlm.nih.gov/pubmed/26466383
http://dx.doi.org/10.1371/journal.pone.0129244

Ejemplares similares

Ejemplares similares