Epigenetic Alterations in Fanconi Anaemia: Role in Pathophysiology and Therapeutic Potential

Fanconi anaemia (FA) is an inherited disorder characterized by chromosomal instability. The phenotype is variable, which raises the possibility that it may be affected by other factors, such as epigenetic modifications. These play an important role in oncogenesis and may be pharmacologically manipul...

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Detalles Bibliográficos
Autores principales: Belo, Hélio, Silva, Gabriela, Cardoso, Bruno A., Porto, Beatriz, Minguillon, Jordi, Barbot, José, Coutinho, Jorge, Casado, Jose A., Benedito, Manuela, Saturnino, Hema, Costa, Emília, Bueren, Juan A., Surralles, Jordi, Almeida, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605638/
https://www.ncbi.nlm.nih.gov/pubmed/26466379
http://dx.doi.org/10.1371/journal.pone.0139740

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