Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

Amyloid formation is historically associated with cytotoxicity, but many organisms produce functional amyloid fibers (e.g., curli) as a normal part of cell biology. Two E. coli genes in the curli operon encode the chaperone-like proteins CsgC and CsgE that both can reduce in vitro amyloid formation...

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Detalles Bibliográficos
Autores principales: Chorell, Erik, Andersson, Emma, Evans, Margery L., Jain, Neha, Götheson, Anna, Åden, Jörgen, Chapman, Matthew R., Almqvist, Fredrik, Wittung-Stafshede, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605646/
https://www.ncbi.nlm.nih.gov/pubmed/26465894
http://dx.doi.org/10.1371/journal.pone.0140194

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